I was thinking that it would be quite the hassle to be a practicing Muslim in the International Space Station. Praying towards Mecca could be quite the problem. However, I think that it is nothing that technology couldn't sort out. I envision fastening yourself into a gyroscopic table-prayer blanket system which would keep you facing Mecca independent of—and in spite of—the the Space Station's earthy rotations.

Just you wait folks, this will be a story someday.